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重组人嗜酸性粒细胞趋化因子-3(CCL26)

Eotaxin-3 (CCL26), human,recombinant, 50 μg

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详细描述:
Eotaxin-3 (CCL26) is a small cytokine that belongs to the CC chemokine family also known as TARC (thymus and activation regulated chemokine). CCL26 is the major eotaxin produced and released by alveolar epithelial cells which is involved in autoregulation of CCR3 receptors and other eotaxins. Eotaxin-3 is involved in immunoregulatory and inflammatory processes. Eotaxin-3 specifically binds and stimulates chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26 exhibits chemotactic activity for normal peripheral blood eosinophils and basophils. It may play a part in the eosinophil accumulation in atopic diseases and is overexpressed in eosinophilic esophagitis, and the expression level correlates with disease severity. Eotaxin-3 is expressed constitutively in thymus, but only briefly in phytohemagglutinin-stimulated peripheral blood mononuclear cells.
Formulation:Sterile-filtered colorless protein solution (0.5 mg/ml) containing phosphate buffered saline (pH 7.4) and 10% glycerol.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-65341 重组人嗜酸性粒细胞趋化因子-3(CCL26) 50 μg/管 商城订购
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