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重组人分泌卷曲相关蛋白4(HEK)

sFRP-4, human, recombinant (HEK), 10 μg

产品概述 技术指标 配套产品 订购信息 精彩视频 相关资料
详细描述:
sFRP-4 (secreted frizzled-related protein 4, SFRP4) belongs to the SFRP family which contains a cysteine-rich domain homologous to the putative Wnt-binding site of frizzled proteins. SFRPs serve as soluble modulators of Wnt signaling. SFRP4 may serve as a regulator of adult uterine morphology and function. SFRP4 increases apoptosis during ovulation possibly via modulation of FZ1/FZ4/WNT4 signaling. SFRP4 also has phosphaturic effects by specifically inhibiting sodiumdependent phosphate uptake. SFRP4 is expressed in proliferative endometrium and several types of ovarian, endometrial and Brest tumors. SFRP4 is expressed in mesenchymal cells and in cardiomyocytes. SFRP4 expression in ventricular myocardium correlates with apoptosis related gene expression. SFRP4 is up-regulated in failing myocardium.
Formulation:Sterile-filtered, white, lyophilized (freeze-dried) powder. The protein was lyophilized from a sterile-filtered (0.2 micron), concentrated protein solution in 0.05 M phosphate buffer and 0.075 M NaCl (pH 7.4).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-65275 重组人分泌卷曲相关蛋白4(HEK) 10 μg/管 商城订购
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