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重组人血栓调节蛋白(CD141;HEK)

Thrombomodulin (CD141), human,recombinant (HEK), 10 μg

产品概述 技术指标 配套产品 订购信息 精彩视频 相关资料
详细描述:
Thrombomodulin (TM, CD141, THBD) is an endothelial cell expressed transmembrane glycoprotein that can form a complex with the coagulation factor, Thrombin. The Thrombomodulin/Thrombin complex converts protein C to its activated form, protein Ca, which in turn proteolytically cleaves and deactivates factor Va and factor VIIIa, two essential components of the coagulation mechanism. This inactivation reduces the generation of additional thrombin and thereby effectively prevents continued coagulation. Reduced levels of Thrombomodulin can correlate with the pathogenesis of certain cardiovascular diseases, such as atherosclerosis and thrombosis. However, the serum levels of the truncated circulating form of Thrombomodulin are typically elevated during inflammation and in the presence of various inflammatory related diseases.
Formulation:Lyophilized from a sterile-filtered protein solution in 10 mM sodium phosphate (pH 7.5).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-65062 重组人血栓调节蛋白(CD141;HEK) 10 μg/管 商城订购
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