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重组人血管内皮细胞生长因子165(HEK)

VEGF-165, human, recombinant,(HEK), 10 μg

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详细描述:
Vascular Endothelial Growth Factor-A was originally isolated from tumor cells and referred to as Tumor Angiogenesis Factor or Vascular Permeability Factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, it may play a role in stimulating vasolidation via nitric oxide-dependent pathways. Alternative splicing of the mRNA for VEGF-A results in several protein isoforms. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95 percent. In contrast to other factors mitogenic for endothelial cells such as FGF-1, FGF-2 and PDGF, VEGF is synthesized as a precursor containing a typical hydrophobic secretory signal sequence of 26 amino acids. Glycosylation is not required for efficient secretion of VEGF. Recombinant human VEGF produced in HEK cells is a glycosylated dimeric polypeptide chain of 165 amino acids and a molecular mass of 40,000 Dalton.
Formulation:White, lyophilized (freeze-dried) powder. The protein was lyophilized from a sterile-filtered (0.2 µm), concentrated (1 mg/ml) protein solution in 20 mM PBS, 150 mM NaCl (pH 7.2) with no additives.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64423 重组人血管内皮细胞生长因子165(HEK) 10 μg/管 商城订购
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