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重组人血管内皮生长因子D(HEK)

VEGF-D, human, recombinant,(HEK), 10 μg

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详细描述:
VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis.
Formulation:Lyophilized from a sterile-filtered (0.2 micron filter) protein solution in PBS.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64414 重组人血管内皮生长因子D(HEK) 10 μg/管 商城订购
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