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重组人Nanog(TAT融合蛋白)

Nanog-TAT, human, recombinant, 20 μg

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详细描述:
Nanog is a regulatory protein that is associated with undifferentiated pluripotent cells. The expression of Nanog, which is suppressed in all adult tissues, is restricted to embryonic stem cells and to certain pluripotent cancer cells. Decreased expression of Nanog is strongly correlated with cell differentiation. Nanog, most likely, acts as an intracellular regulator, which helps maintain pluripotency and self renewal via a STAT3 independent pathway. The introduction of Nanog, along with Sox2, Oct4, Lin28, into primary human fibroblasts wassufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology and gene expression. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells.
Formulation:Sterile-filtered, colorless solution containing PBS and 50 mM arginine.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64326 重组人Nanog(TAT融合蛋白) 20 μg/管 商城订购
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