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重组人基质金属蛋白酶2(大肠杆菌)

MMP-2, human, recombinant,(E. coli), 10 μg

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详细描述:
Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by upregulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 produced in E. coli is a 64.7 kDa non-glycosylated, single polypeptide chain consisting of 576 amino acids (aa 110-660), fused to a 25 amino acid His-tag at the N-terminus and purified using proprietary chromatographic techniques.
Formulation: Sterile-filtered colorless solution (0.25 mg/ml) containing 20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl and 10% glycerol.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64120 重组人基质金属蛋白酶2(大肠杆菌) 10 μg/管 商城订购
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