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重组人基质金属蛋白酶13

MMP-13, human, recombinant, 2.5 μg

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详细描述:
Latent recombinant human pro-collagenase (MMP-13) also called collagenase-3 truncated from C-terminal. Matrix Metalloproteinase-13 (MMP-13) is an enzyme that is a member of the MMP extracellular protease family. Extracellular protease enzymes, by virtue of their broad substrate specificities1, play a role in both normal and disease states of tissue proliferation. Among the targets of MMP-13 are collagen, gelatin, entactin, pro-TNF-alpha, and chemokine SDF-11-4. MMP-13 is found in its latent form as a 52-56 kDa glycosylated proenzyme. Upon cleavage the 22-46 kDa5 MMP-1 becomes active in extracellular matrix remodeling. Because of the prominent role that MMP-1 plays in cell migration and metastasis, it is an important target for inhibition screening.
Formulation: Sterile-filtered, clear solution (0.5 mg/ml) in 20 mM Tris-HCl buffer (pH 8.0), containing 0.15 M NaCl, 10% glycerol and 1 mM DTT.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64118 重组人基质金属蛋白酶13 2.5 μg/管 商城订购
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