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重组人基质金属蛋白酶3

MMP-3, human, recombinant,(HEK), 10 μg

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详细描述:
MMP-3 enzyme is also known as Stromelysin-1 or as Transin-1 which hydrolyzes natural collagen at physiological pH and temperature. MMP-3 hydrolyzes components of the extracellular matrix like proteoglycan, laminin, fibronectin, gelatin and collagen types III, IV and IX. It also activates pro-MMP-9 and pro-MMP-8 and superactivates plasmin activated MMP-1. MMP-3 is secreted as a latent proenzyme and is activated by a variety of proteinases, e.g. plasmin, trypsin, chymotrypsin, cathepsin G or human neutrophil elastase. MMP-3 was found to be capable of activating the precursor of IL-1 beta.|Human recombinant MMP-3 produced in HEK293 cells is a proform of the Human MMP3 [Tyr18-Cys477 (Lys45Glu)] and fused with a polyhistidine tag at the C-terminus. It has an MW of 52 kDa and has been purified by using proprietary chromatographic techniques.
Formulation: Sterile-filtered (0.2 µm), colorless solution (0.30 mg/ml) in 20 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35 (pH 7.5).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64105 重组人基质金属蛋白酶3 10 μg/管 商城订购
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