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重组人基质金属蛋白酶2(HEK)

MMP-2, human, recombinant,(HEK), 10 μg

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详细描述:
Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by upregulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 produced in HEK293 cells is a proform of the Human MMP-2 (Ala30-Cys660) and fused with a ployhistide tag at the C-terminus, having a MW of 71kDa.
Formulation: The MMP-2 is supplied as a 0.2 µm sterile-filtered solution in Tris, NaCl and Brij35 (pH 7.4).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-64103 重组人基质金属蛋白酶2(HEK) 10 μg/管 商城订购
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