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重组人肿瘤坏死因子α（植物）

TNF-alpha, human, recombinant,(Plant), 50 μg

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详细描述：
TNF-alpha (Tumor necrosis factor alpha), a member of the TNF ligand superfamily, is among others, secreted by macrophages, activated monocytes, neutrophils, T-cells, B-cells and natural killer cells stimulated by bacterial lipopolysaccharides. TNF-alpha shows approximately 30% homology with TNF-beta. TNF-alpha plays an important role in the regulation of immune cells. TNF-alpha has many biological activites, including a cytotoxic effect to various tumor cells, causes inflammation, cellular proliferation and plays a critical role in mediating resistance to bacterial infections. Human and murine TNF-alpha show approximately 79% homolgy and human TNF-alpha is active on murine cells with a slightly reduced specific activity. Recombinant human TNF-alpha produced in plant is a 19.6 kDa protein containing 158 amino acid residues and a 16 a.a. histidine-based tag for a total length of 174 a.a. The recombinant protein migrates as two bands with an apparent molecular mass of 24 kDa in SDS-PAGE. Recombinant human TNF-alpha is produced in the endosperm tissue of barley grain (Hordeum vulgare), that exhibits up to 50 times less protease activity than E.coli or mammalian cells. Barley seed is void of any human or animal viral contaminants that could jeopardize your cell culture.
Formulation: Sterile filtered through a 0.2 µm filter. Lyophilized from PBS (pH 7.2).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-63720A 重组人肿瘤坏死因子α（植物） 50 μg/管 商城订购
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