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重组人脑多巴胺神经营养因子

CDNF, human, recombinant, 20 μg

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详细描述:
CDNF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain nonneuronal tissues. It has been shown to promote survival, growth and function of dopamine specific neurons. CDNF and its structural homolog MANF, each contain an N terminal saposinlike lipid binding domain, and a carboxyl-terminal domain, which is not homologous to previously characterized protein structures. CDNF and MANF can prevent 6-OHDA induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson disease. Recombinant human CDNF produced in E. coli is a single, non-glycosylated polypeptide chain of 161 amino acids with a molecular mass of 18.5 kDa. It has been purified by proprietary chromatographic techniques.
Formulation: Lyophilized from a sterile-filtered, concentrated protein solution in 1xPBS (pH 7.4).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-63408 重组人脑多巴胺神经营养因子 20 μg/管 商城订购
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