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重组人CD14(HEK)

CD14, human, recombinant (HEK), 50 μg

产品概述 技术指标 配套产品 订购信息 精彩视频 相关资料
详细描述:
CD14 (also known lipopolysaccharide [LPS] receptor) is expressed strongly on monocytes and macrophages and weakly on the surface of neutrophils. CD14 (1-201 a.a.) is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentrations as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wildtype CD14 is the 50 kDa protein. Recombinant sCD14 is a 341 amino acid (aa 20-352) monomeric glycoprotein fused to an 8 amino acid His-tag at the C-terminus and purified using proprietary chromatographic techniques.
Formulation: Lyophilized from a sterile-filtered (0.2 micron filter) protein solution in 20 mM phosphate buffr (pH 7.4) and 150 mM NaCl.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-63325 重组人CD14(HEK) 50 μg/管 商城订购
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