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重组人可溶性NF-κB受体激活剂（TNFRSF11A）

sRANK Receptor, human,recombinant, 100 μg

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详细描述：
RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate naïve T cell proliferation and to promote the survival of RANK + T cells. RANK is also expressed in a variety of tissues including skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.1 kDa single, non-glycosylated polypeptide of 174 amino acid residues. Recombinant sRANK Receptor has been purified using proprietary chromatographic techniques.
Formulation: Lyophilized (freeze-dried), sterile powder. Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM Tris-HCl (pH 8.0) and 150 mM NaCl.
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C-63201 重组人可溶性NF-κB受体激活剂（TNFRSF11A） 100 μg/管 商城订购
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