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重组人血小板衍生生长因子BB（HEK）

PDGF-BB, human, recombinant (HEK), 10 μg

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详细描述：
PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene. Human recombinant PDGF-BB produced in HEK cells is a glycosylated homodimer, having a molecular weight of 29-32 kDa due to glycosylation. The recombinant PDGF-BB has been purified using proprietary chromatographic techniques.
Formulation: White (freeze-dried) powder. Lyophilized from a sterile-filtered (0.2 µm) protein solution in 50 mM acetate (pH 3.5) and 500 mM NaCl.
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货号 名称 单位 购买
C-63023 重组人血小板衍生生长因子BB（HEK） 10 μg/管 商城订购
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