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重组人白细胞介素15（HEK）

IL-15, human, recombinant (HEK), 10 μg

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详细描述：
Human Interleukin-15 is a potent lymphoid cell growth factor, which exerts its biological activities primarily on T cells. This cytokine and Interleukine-2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL-2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. Human recombinant Interleukin-15 produced in HEK cells is a glycosylated monomer, having a molecular weight of 12.8 kDa due to glycosylation. The recombinant IL-15 has been purified using proprietary chromatographic techniques.
Formulation: White (freeze-dried) powder. Lyophilized from a sterile-filtered (0.2 µm) protein solution in phosphate buffered saline (pH 7.4) with 10% (w/v) trehalose.
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货号 名称 单位 购买
C-62513 重组人白细胞介素15（HEK） 10 μg/管 商城订购
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