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重组人胰岛素样生长(HEK)

IGF-BP4, human, recombinant (HEK), 20 μg

产品概述 技术指标 配套产品 订购信息 精彩视频 相关资料
详细描述:
Insulin-like growth factor-binding protein 4 (IGF-BP4) belongs to the insulin-like growth factor binding protein (IGFBP) family. It includes an IGF-BP domain and a thyroglobulin type-I domain and binds both insulin-like growth factors (IGFs) I and II. IGF-BP4 circulates in the plasma in both glycosylated and non-glycosylated forms. It can either inhibit or enhance the biological activities of IGF, or act in an IGF independent manner. IGF-BP4 is exceptional since it consistently inhibits several cancer cells in vivo and in vitro, suggesting that it may function as an apoptotic factor. IGFB-P4 is produced by all colon cancer cells. Binding of IGFBP-4 prolongs the half-life of the IGFs and changes their interaction with cell surface receptors. Human recombinant IGF-BP4 (amino acids Asp22- Glu258) is produced in HEK293 cells and fused with a polyhistidine tag at the C-terminus
Formulation:White, lyophilized (freeze-dried) powder. Lyophilized from a sterile-filtered (0.2 micron filter) protein solution in PBS (pH 7.2) with no additives
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-60851 重组人胰岛素样生长(HEK) 20 μg/管 商城订购
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