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重组人成纤维细胞生长因子23

FGF-23, human, recombinant, 20 μg

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详细描述：
FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of FGF-23 was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in FGF-23 have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. Human recombinant FGF-23 produced in E. coli is a 25.5 kDa globular protein containing 228 amino acid residues.
Formulation:Sterile-filtered through a 0.2 micron filter and lyophilized from a protein solution in 10 mM sodium acetate (pH 6.0) and 0.1 M arginine.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-60501 重组人成纤维细胞生长因子23 20 μg/管 商城订购
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