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重组人成纤维细胞生长因子12

FGF-12, human, recombinant, 10 μg

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详细描述:
FGF-12 is part of the Fibroblast Growth Factor (FGF) family which has a vast mitogenic and cell survival functions, and play a role in a range of biological activities, among them are embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF-12 doesn’t obtain the N-terminal signal sequence present in the majority of the FGF family members, but it contains clusters of basic residues that act as a nuclear localization signal. When transfected into mammalian cells, FGF-12 accumulated in the nucleus, but was not secreted. FGF-12 is involved in nervous system development and function. FGF-12 binds to IB-2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and is also involved in intracellular signaling and ion exchange.
Formulation:The FGF-12 solution (1 mg/ml) contains 20 mM Tris (pH 7.5), 1 mM DTT, 2 mM EDTA and 10% glycerol.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-60417 重组人成纤维细胞生长因子12 10 μg/管 商城订购
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