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重组人碱性成纤维细胞生长因子2(耐热)

FGF-2 (FGF-b), human,recombinant (thermostable), 10 μg

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详细描述:
Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis,tissue repair, tumor growth and invasion.FGF-basic (thermostable) is a stabilized form of FGF-2 which enables a novel method to produce FGF2-dependent cell cultures more efficiently, having less media changes. FGF-basic (thermostable) can maintain its biological activity even after five days at 37°C. The increase in the stability of FGF-2 in cell-culture enables a more homogenous, undifferentiated stem cell culture, while saving scientists crucial time and money, as frequent supplementation of FGFbasic and the everyday medium change is not necessary. The thermostable FGF-2 is a hyperstable protein and the thermal stability of the protein is increased by 15°C compared to the wild-type FGF-2 with a more than 5-times prolonged half-life in human cell culture incubated at 37°C. The FGF-2 (thermostable) protein is engineered with fully retained biological function and has no harmful stabilizing additives. Human Recombinant thermostable FGF-2 produced in E. coli is a single, non-glycosylated, polypeptide chainof 175 amino acids including a 20 aa His tag and thrombin cleavage recognition site at the N-terminus. The total calculated molecular mass is 19.4 kDa. It has been purified using proprietary chromatographic techniques.
Formulation: White (freeze-dried) powder. Lyophilized from a sterile-filtered protein solution (1 mg/ml) containing 20 mM potassium phosphate buffer and 750 mM sodium chloride (pH 7.5).
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-60241 重组人碱性成纤维细胞生长因子2(耐热) 10 μg/管 商城订购
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