详细描述：
The fasting-induced adipose factor (FIAF, ANGPTL4, PGAR, HFARP) was identified as an adipocytokine up-regulated by fasting, by peroxisome proliferator-activated receptor agonists, and by hypoxia. At the protein level, in human and mouse blood plasma, FIAF was found to be present both as a native protein and in a truncated form. Differentiation of mouse 3T3-L1 adipocytes was associated with the production of truncated FIAF, whereas in human white adipose tissue and SGBS adipocytes, only the native FIAF could be detected. Interestingly, the truncated FIAF was produced by human liver. Experimental data suggest that FIAF is mainly presented in human blood plasma in a truncated form (FIAF-S2), whose level is increased by fenofibrate treatment. Recombinant human Angiopoietin-like Protein 4, expressed with an Nterminal His-tag, is a 25 kDa polypeptide containing 204 amino acid residues of the human ANGPTL4 and 16 additional amino acid residues.
Formulation: Sterile-filtered, white, lyophilized (freeze-dried) powder. Lyophilized from a 0.5 mg/ml solution in 0.05 M acetate buffer (pH 4).
