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重组人白血病抑制因子（植物）

LIF, human, recombinant,(Plant), 50 μg

产品概述 技术指标 配套产品 订购信息 精彩视频 相关资料
详细描述：
Leukemia inhibitory factor (LIF) is a pleiotropic lymphoid factor belonging to the interleukin-6 family of cytokines. It was initially described as a factor inhibiting the proliferation of myeloid leukemia cells and inducing their differentiation into macrophages. Other activities of LIF include inhibition of adipogenesis and roles in cholinergic neuron differentiation, hematopoeisis, inflammation and bone metabolism. LIF inhibits the differentiation of embryonic stem cells, it is therefore important in ES cell culture. Human and mouse LIF share 78% amino acid homology, the human version is equally active on human and mouse cells but murine LIF is not active on human cells. Recombinant human LIF contains 180 amino acids and a 16 a.a. histidine-based tag for a total length of 196 a.a. and has a predicted molecular mass of 21.8 kDa including his-tag. As a result of glycosylation, the recombinant protein migrates with an apparent molecular mass of 25-30 kDa in SDS-PAGE. Recombinant human LIF is produced in the endosperm tissue of barley grain (Hordeum vulgare), that exhibits up to 50 times less protease activity than E. coli or mammalian cells. Barley seed is void of any human or animal viral contaminants that could jeopardize your cell culture. Purified product carries no pyrogenic or pro-inflammatory contaminants, as assayed with monocyte activation test using Human 10-plex Cytokine Assay measuring IL-6, TNF-alpha and IL-1 beta induction.
Formulation: Lyophlized from a sterile-filtered (0.2 µm) protein solution in PBS (pH 7.2).
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C-60051A 重组人白血病抑制因子（植物） 50 μg/管 商城订购
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