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重组人载脂蛋白A1

APO-A1, human, recombinant, 100 μg

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详细描述：
Apo-A1 is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. Apo-A1, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This Apo-1 ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the ͞good cholesterol.͟The therapeutic potential of Apo-A1 has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of Apo-A1 (called Apo-A1 Milano). The availability of recombinant normal Apo-A1 should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Recombinant human Apo-A1 is a 20.3 kDa protein of 264 amino acid residues (aa 25-267). It is fused to a 20 a.a. His-tag at the N-terminus and has been purified by proprietary chromatographic techniques.
Formulation: Sterile-filtered, colorless protein solution (1 mg/ml) in 20 mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
货号 产品名称 品牌 购买
货号 名称 单位 购买
C-60016 重组人载脂蛋白A1 100 μg/管 商城订购
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